Bioinformatics for Breeding - course at the Earlham Institute, Norwich, UK
"What is the workshop about?
The increasing number of genomic tools and resources which facilitate large-scale analysis of genotypes and traits are leading to novel, quicker approaches to breeding. This course will introduce participants to the sequencing-based methods and bioinformatics tools available to apply genomic approaches to breeding.
The practical course will feature a collection of methods and bioinformatics tools fundamental for modern breeding, especially for crops. Next generation sequencing (NGS) has made large collections of open-source diversity genomic data possible, such as SNPs, that can be used as molecular markers for breeding. Combined with phenotypes, genome-wide association studies provide breeders with an understanding of the molecular basis of complex traits.
What will it cover?
- SNP calling/discovery and SNPs effects and context
- NGS techniques for genotyping
- Genetic markers, linkage analysis, and genetic maps
- High-throughput phenotyping and image analysis
- Association mapping (GWAS)
- Genome-wide predictions, modelling and simulations
- Genomic selection
The course is aimed at researchers or pre-breeders working in plant (or animal) improvement and interested in applying NGS approaches in the early future, as well as to plant bioinformaticians with basic knowledge about crop breeding."